Psoriasis Help Organisation - Online Psoriasis Forum

Vitamin D analogues

The introduction of calcipotriol in the early 90s has provided an alternative to topical steroids, tars and dithranol. Calcipotriol has shown equal or superior efficacy to other agents and is cosmetically more acceptable and generally well tolerated.

Local irritation does occur; however these agents are not associated with the cutaneous atrophy of corticosteroids or the messiness of tars and dithranol.

DOVONEX (Calcipotriol) Leo Laboratories

Dovonex is the Tradename of three products which are manufactured from a derivative of Vitamin D. There is a Scalp Application, a Cream and an Ointment for the body.

The makers say it is NOT suitable for the treatment of the facial area (or other tender areas of the body), as it might have an irritant effect on some people in these areas.

It is also not indicated for Pustular Psoriasis - the type that presents as blisters under the skin, on the palms of the hands and soles of the feet. It is obtainable on prescription only, and cannot be bought over-the- counter.

Discontinuation of Dovonex Ointment
LEO pharma UK have announced that they are discontinuing the supply of the ointment formulation of Dovonex on 16th April 2007. In view of current and future availability of alternative products for the topical treatment of plaque psoriasis, the clinical usefulness and commercial viability of this product is judged to be too limited to justify its continued supply by LEO Pharma. Alternative formulations such as Dovonex Cream and Scalp Solution will continue to be available. The discontinuation has not resulted from any safety or quality concerns.

CURATODERM (Taealcitol) Crookes Pharmaceutical

This product for mild to moderate plaque psoriasis was launched in 1996. It is on prescription only. It is the first Vitamin D treatment for Psoriasis that has a once daily application. A single application - preferably at night time - lasts up to 24 hours. This treatment can be used safely on the face and on soft areas of the body.